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Effect of IFN-λ1 treatment on replication of the IVA (a) and AdV (b) genomes. Viral RNA yields (normalized to GAPDH) were determined after infection of A549 cells (untreated or IFN-λ1 treated at 500 ng/mL) with IVA or AdV (both 0.1 MOI). All data are representative of at least three independent experiments. p value significance levels were determined by unpaired nonparametric Mann–Whitney test (U-test). *—p value = 0.0286. Data are shown as mean ± SD.
