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. 2021 Jul 25;13(8):1448. doi: 10.3390/v13081448

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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HCV virus genotype effects on frequency and absolute numbers of regulatory T cells in HCV-infected and HCV/HIV-coinfected patients. Treg-related parameters analyzed in context of frequencies: Foxp3⁺ in CD4⁺ (a) and CD4⁺CD25⁺CD127⁻ T cells (b), CD25⁺CD127⁻Foxp3⁺ (c) and CD25+CD127- (d) within CD4⁺ T cell pool; and absolute numbers: Foxp3⁺ (e), CD25⁺CD127⁻Foxp3⁺ (f), CD25+CD127- (g) CD4⁺ lymphocytes, and total CD4⁺ cells (h). Significant changes in relation to healthy controls indicated directly above specific group column; additional differences distinguished with lines connecting significantly different groups.