Table 4.
Distribution of RVDG-mCherry afferents to KNDy cells, as expressed by the mean ± SEM percentage of total mCherry cells, in PNV male (n = 6), PNV female (n = 6), and PNA female (n = 7) mice in the brain
| Brain region | PNV male | PNV female | PNA female |
|---|---|---|---|
| Septal nucleus | 1.5 ± 0.3 | 1.6 ± 0.3 | 1.3 ± 0.5 |
| Bed nucleus of the stria terminalis | 1.5 ± 0.2 | 1.7 ± 0.3 | 1.0 ± 0.1 |
| Preoptic area | 1.5 ± 0.2 | 2.2 ± 0.3 | 1.1 ± 0.3 b |
| Ventromedial preoptic nucleus | 1.9 ± 0.3 | 1.7 ± 0.3 | 0.8 ± 0.2 a |
| Organum vasculosum of the stria terminalis | 1.3 ± 0.3 | 0.7 ± 0.2 | 0.7 ± 0.3 |
| Medial preoptic nucleus | 6.9 ± 1.1 | 5.4 ± 0.7 | 4.2 ± 0.8 |
| Anteroventral periventricular nucleus | 5.6 ± 0.6 | 8.4 ± 0.5a | 4.7 ± 0.7 b |
| Periventricular nucleus | 1.5 ± 0.2 | 2.9 ± 0.4 | 2.2 ± 0.6 |
| Paraventricular nucleus | 6.3 ± 1.1 | 4.1 ± 0.4 | 4.2 ± 1.2 |
| Lateroanterior hypothalamic nucleus | 1.3 ± 0.2 | 1.7 ± 0.2 | 1.1 ± 0.3 |
| Anterior hypothalamic area | 3.1 ± 0.8 | 6.2 ± 0.9 a | 1.8 ± 0.3 b |
| Ventromedial hypothalamus | 3.1 ± 0.5 | 3.7 ± 0.6 | 3.1 ± 0.3 |
| Supraoptic nucleus | 4.9 ± 1.1 | 2.7 ± 0.4 | 2.6 ± 0.9 |
| Accessory groups of the supraoptic nucleus | 13.0 ± 2.8 | 8.6 ± 1.2 | 7.0 ± 2.6 |
| Arcuate nucleus | 26.1 ± 2.1 | 20.2 ± 3.0 | 43.5 ± 3.3 a,b |
| Dorsomedial hypothalamic nucleus | 3.3 ± 0.9 | 4.5 ± 0.6 | 3.7 ± 2.0 |
| Lateral hypothalamic area | 1.8 ± 0.2 | 2.9 ± 0.5 | 1.3 ± 0.3 b |
| Posterior hypothalamic area | 1.7 ± 0.5 | 4.1 ± 1.6 | 2.4 ± 1.6 |
| Premammillary nucleus | 6.6 ± 1.0 | 5.9 ± 0.6 | 6.8 ± 1.9 |
| Tuberal nucleus | 3.2 ± 0.7 | 4.0 ± 0.6 | 2.6 ± 0.7 |
| Supramammilary nucleus | 0.8 ± 0.2 | 2.4 ± 0.9 | 1.1 ± 0.4 |
| Zona incerta | 0.6 ± 0.2 | 1.8 ± 0.4 | 1.7 ± 1.1 |
| Paraventricular thalamic nucleus | 0.7 ± 0.1 | 1.1 ± 0.3 | 0.2 ± 0.1 |
| Medial amygdala | 0.7 ± 0.2 | 1.0 ± 0.1 | 0.5 ± 0.2 |
| Amygdalohippocampal area | 0.9 ± 0.3 | 0.4 ± 0.1 | 0.4 ± 0.2 |
Abbreviations: KNDy, kisspeptin/neurokinin B/dynorphin; PNA, prenatal androgen-treated; PNV, prenatal vehicle; RVDG, glycoprotein-deleted rabies virus; SEM, standard error of the mean.
a significantly different to PNV male,
b significantly different to PNV female.