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. 2021 Aug 28;12(4):776–784. doi: 10.1007/s13193-021-01419-0

Table 4.

Summary of outcomes for postoperative therapy in patients with esophageal cancer after neoadjuvant therapy and surgery

Reference (first author) Year Histology Neoadjuvant treatment Adjuvant treatment OS p
Drake et al. [24] 2019 AC CT CT/observation

Median

31.2 M/24.0 M

0.031
Semenkovich et al. [25] 2019 AC/SCC RT CT or CRT/observation

Median

2.6 Y/2.3 Y

0.02
Yan et al. [26] 2019 SCC CT CT/observation

5-Y OS

62.4%/68.6%

0.359
Our studya 2020 SCC CT CT/observation

Median

Not reached/20.1 M

0.040

AC adenocarcinoma, SCC squamous cell carcinoma, CT chemotherapy, RT radiotherapy, CRT chemoradiotherapy, M month, Y year

aThoracic esophageal cancer patients with two or more positive lymph nodes