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. 2021 Aug 24;16:5693–5712. doi: 10.2147/IJN.S314472

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© 2021 Ezzeldeen et al.

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3-D surface response plots showing the relative effects of independent variables on (A) particle size, (B) PDI, (C) Zeta-potential, (D) drug EE%, and (E) desirability.