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. 2021 Aug 24;16:5693–5712. doi: 10.2147/IJN.S314472

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© 2021 Ezzeldeen et al.

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Intracellular uptake of fluorescein-loaded TFs in nonactivated and TAM- or TAF-activated melanoma cells upon combination with TME remodeling agents (metformin and collagenase) (A). Cytotoxicity of HKTs in nonactivated (B), TAM-activated (C), and TAF-activated (D) B16F10 melanoma cells upon combination with TME remodeling agents (metformin and collagenase). *P<0.05; *; p<0.01.