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. 2021 Aug 24;15:3697–3708. doi: 10.2147/DDDT.S321879

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© 2021 Wang et al.

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PR inhibits ECM accumulation in UUO mice. (A–H) According to the results of Wb and IHC, PR significantly inhibited the expression levels of the fibrosis markers α-SMA, VIM and COL I in the kidney of UUO mice. Scale bar = 50μm. ^##P<0.01, ^###P<0.001, vs Sham group; **P<0.01, vs UUO group; ^†P<0.05, ^††P<0.01, vs UUO + PRL group.