Table 1.

Multivariate Cox Regression Analysis of Clinical Factors and Hub Genes

	Univariate Cox			Multivariate Cox
	Log (HR)	95% CI	P	Log (HR)	95% CI	P
Age	0.1012	−0.5091; 0.7115	n.s.	0.2830	−0.3472; 0.9133	n.s.
Gender	0.0518	−0.4836;, 0.5873	n.s.	0.1129	−0.4392; 0.6649	n.s.
Tumor stage	0.9370	0.0885;, 1.7854	0.03	1.2712	0.3904; 2.1520	0.004
Risk score	0.5552	0.3628, 0.7477	<0.001	0.6304	0.4274; 0.8335	<0.001
CR2	0.0589	0.0275, 0.0903	<0.001	0.2046	0.0236; 0.3856	0.03
KRT85	2.0704	0.9047, 3.2361	<0.001	2.5114	1.0993; 3.9234	<0.001
LGI4	0.1448	0.0054;, 0.2842	0.04	0.1983	0.0131; 0.3835	0.04
NPAS4	3.8793	0.4403, 7.3182	0.03	−19.9721	−38.0522, −1.8921	0.03
SP140	0.4395	0.2049; 0.6742	<0.01	0.7001	0.1804; 1.2197	0.008
RUVBL1	0.0830	0.0113; 0.1547	0.02	0.1327	0.0267; 0.2388	0.01
CDH4	2.4616	1.1367; 3.7865	<0.001	1.9639	0.1010; 3.8268	0.04