Table 3.

HRs and 95% CIs for Quartiles of WASO and SE Associated with Ischemic Stroke

	Univariable Models		Multivariable Adjusted†		Multivariable Adjusted‡
All Subjects	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
WASO
Fourth quartile (>80 min)	4.996 (2.600–9.597)	<0.001	3.298 (1.608–6.768)	0.001	3.771 (1.805–7.877)	<0.001
Third quartile (49.0min–80min)	3.299 (1.675–6.496)	0.001	2.749 (1.317–5.738)	0.007	3.009 (1.433–6.317)	0.004
Second quartile (30.0min–48.5min)	3.005 (1.519–5.945)	0.002	2.933 (1.392–6.183)	0.005	3.108 (1.470–6.568)	0.003
First quartile (<30.0 min)	1(Ref)		1(Ref)		1(Ref)
Sleep efficiency
First quartile (<80.0%)	3.726 (2.174–6.386)	<0.001	2.210 (1.241–3.936)	0.007	2.220 (1.244–3.960)	0.007
Second quartile (80.0–84.9%)	2.467 (1.332–4.569)	0.004	1.859 (0.970–3.564)	0.062	1.829 (0.952–3.514)	0.070
Third quartile (85.0–89.9%)	1.866 (1.017–3.423)	0.044	1.443 (0.762–2.732)	0.261	1.457 (0.769–2.760)	0.248
Fourth quartile (≥90%)	1(Ref)		1(Ref)		1(Ref)

Notes: ^†Adjusted by age, gender, smoking status, race, body mass index, prevalent hypertension and diabetes mellitus, apnea-hypopnea index, benzodiazepine use, alcohol use. ^‡Adjusted by ^†plus sleep duration.

Abbreviations: 95% CI, 95% confidence interval; HR, hazard ratio; WASO, wake after sleep onset.