Figure 7.

Effect of curcumin on LPS/IFNγ-induced macrophage polarization in BMMs. Concentration of TNF-α (a), IL-1β (b), IL-6 (c), and IL-10 (d) in cell culture medium of BMMs after being stimulated with different stimuli. Representative flow cytometry data of activated macrophages after being stimulated with different stimuli (e) and quantification of M1 (iNOS+F4/80+) (f) and M2 (Arg+F4/80+) (g) macrophages. Each experiment was repeated 3 times independently. Data were shown as the mean ± SEM. ∗ was P < 0.05 vs. the LPS+IFNγ stimulation group, and # was P < 0.05 vs. the unstimulated group. P value was calculated by post hoc comparisons.