Table 2.
Effect of curcumin on echocardiographic parameters of MI mice at 3 months after myocardial infarction.
| Sham (n = 6) | MI (n = 7) | MI+Cur (n = 9) | ||
|---|---|---|---|---|
| Heart rate (bmp) | 446 ± 18 | 468 ± 12 | 472 ± 15 | |
| LVDd (mm) | 4.08 ± 0.05 | 5.62 ± 0.13∗ | 5.36 ± 0.11∗# | |
| LVDs (mm) | 3.12 ± 0.03 | 5.62 ± 0.15∗ | 4.93 ± 0.18∗# | |
| FS (%) | 26.0 ± 1.5 | 6.9 ± 1.0∗ | 11.2 ± 1.8∗# | |
| LVEF (%) | 52.3 ± 0.5 | 13.8 ± 1.5∗ | 21.23 ± 2.3∗# | |
| WThd, septum (mm) | Remote | 0.98 ± 0.08 | 0.85 ± 0.15∗ | 0.90 ± 0.12∗ |
| Border | 0.92 ± 0.05 | 0.43 ± 0.09∗ | 0.44 ± 0.12 | |
| WThd, free wall (mm) | Remote | 0.91 ± 0.03 | 1.02 ± 0.08∗ | 1.01 ± 0.07 |
| Border | 1.01 ± 0.06 | 0.48 ± 0.11∗ | 0.51 ± 0.09 | |
| WThs, septum (mm) | Remote | 1.12 ± 0.15 | 0.85 ± 0.08∗ | 1.05 ± 0.08∗# |
| Border | 1.11 ± 0.08 | 0.49 ± 0.06∗ | 0.52 ± 0.11 | |
| WThs, free wall (mm) | Remote | 1.15 ± 0.07 | 1.08 ± 0.05 | 1.14 ± 0.07 |
| Border | 1.18 ± 0.09 | 0.48 ± 0.02∗ | 0.57 ± 0.10∗# |
Data were shown as the mean ± SEM. ∗ was P < 0.05 vs. the sham group, and # was P < 0.05 vs. the MI group. And P value was calculated by post hoc comparisons. LVDd: left ventricular (LV) dimension at end diastole; LVDs: left ventricular (LV) dimension at end systole; FS: fractional shortening; LVEF: left ventricular (LV) ejection fraction; WThd: wall thickness at end diastole; WThs: wall thickness at end systole.