Table 3.

Main Determinants Associated with Non-Adherence

Main Identified Determinants Associated with Non-Adherence
	Associated with Higher Non-Adherence	Associated with Lower Non-Adherence
Age	Younger age (≤ 50 years)	Older age
Sex	Female sex	Male sex
Ethnicity	African American Hispanic	Caucasian
Marital Status	Divorced Separated Widowed Single	Married
Habits	Smoking habits	Alcohol drinking habits
Comorbidities	Chronic obstructive pulmonary disease Alzheimer disease/dementia Depression Diabetes Anxiety Hepatic disease Chronic kidney disease Peripheral vascular disease Heart failure	Higher number of comorbidities Higher number of cardiovascular risk factors Present heart disease Hypertension
Medications	New users of lipid-lowering medications Patients presenting side effects or concerns about them Higher duration of lipid-lowering treatment	Patients taking β-blockers Patients taking antiplatelets
Cardiovascular diseases and interventions		History of cardiovascular disease events History of cardiac intervention or revascularization procedure
Healthcare services utilization		Higher healthcare services utilization Patients treated in cardiology Patients treated in family medicine Having health insurance Higher number of follow-up visits
Other determinants	Unemployment Bad doctor–patient relationship