Table 2.

Cox Regression Analysis of Predictors of Acute Kidney Injury Among Cohorts of Type 2 Diabetes Patients at Chronic Follow-Up Clinic of University of Gondar Comprehensive Specialized Hospital, from January 1, 2014, to December 31, 2019 (n= 420)

Variables	Survival Status		CHR(95% CI)	Adjusted AHR(95% CI)
	Event	Censored
Residence
Urban	55	188	1.5(0.95, 2.36)	0.33(0.78, 2.17)
Rural	28	149	1.00	1.00
Smoking habit
Never smoker	10	14	0.45(0.23, 0.86)	1.06(0.49, 2.30)
Smoker	73	323	1.00	1.00
Alcohol use
Yes	44	88	2.746(1.783, 4.23)	1.60(0.97, 2.65)
No	39	249	1.00	1.00
Hypertension
Yes	73	154	7.08(3.65, 13.71)	2.87(1.20, 6.90)*
No	10	181	1.00	1.00
Congestive heart failure
Yes	53	52	6.61(4.22, 10.37)	2.89(1.62, 5.13)*
No	30	285	1.00	1.00
Chronic kidney disease
Yes	30	8	9.03(5.71, 14.27)	2.92(1.56, 5.48)*
No	53	329	1.00	1.00
Infection
Yes	68	175	3.71(2.12, 6.50)	1.82(0.95, 3.52)
No	15	162	1.00	1.00
Stroke
Yes	14	19	2.71(1.53, 4.82)	1.85(0.95, 3.58)
No	69	318	1.00	1.00
Diabetic nephropathy
Yes	43	25	7.13(4.62, 10.99)	2.04(1.13, 3.68)*
No	40	312	1.00	1.00
Diabetic ketoacidosis
Yes	24	62	1.83(1.14, 2.95)	1.58(0.91, 2.73)
No	59	275	1.00	1.00
Diabetic retinopathy
Yes	14	20	2.27(1.28, 4.04)	0.80(0.38, 1.67)
No	69	317	1.00	1.00
Diabetic foot ulcer
Yes	26	56	2.03(1.28, 3.23)	1.10(0.61, 1.97)
No	57	281	1.00	1.00
Family history of DM
Yes	31	81	1.84(1.18, 2.88)	0.79(0.46, 1.36)
No	52	256	1.00	1.00
Beta blockers
Yes	13	18	2.59(1.43, 4.69)	1.05(0.53, 2.08)
No	70	319	1.00	1.00
Calcium channel blocker
Yes	41	61	3.70(2.40, 5.70)	1.22(0.72, 2.08)
No	42	276	1.00	1.00
ACE inhibitor/ARBs
Yes	51	124	2.37(1.52, 3.69)	0.85(0.48, 1.48)
No	32	213	1.00	1.00
Diuretics
Yes	25	53	1.96(1.22, 3.13)	0.66(0.37, 1.17)
No	58	284	1.00	1.00
Aminoglycosides
Yes	14	21	2.24(1.26, 3.97)	1.14(0.59, 2.22)
No	69	315	1.00	1.00
NSAIDs
Yes	41	72	2.83(1.84, 4.35)	1.17(0.64, 2.14)
No	42	265	1.00	1.00
Statin exposure
Yes	53	139	2.24(1.43, 3.51)	0.94(0.51, 1.72)
No	30	197	1.00	1.00

Note: *Significant at p<0.05.