. 2021 Jun 26;10(13):e019864. doi: 10.1161/JAHA.120.019864

Table 2.

Functional Status Measures at Baseline Stratified by Concordant and Discordant Group Assignment

Characteristic	Favorable V_E/VCO₂ Slope		Unfavorable V_E/VCO₂ Slope		P Value^*
Characteristic	High KCCQ‐CS, Concordant–Lower Severity, N=566, 27.4%	Low KCCQ‐CS, Discordant: Symptom Magnifier, N=480, 23.3%	High KCCQ‐CS, Discordant: Symptom Minimizer, N=465, 22.6%	Low KCCQ‐CS, Concordant–Higher Severity, N=551, 26.7%	P Value^*
Distance of 6 min walk, m, N=2016	411 (350–463)	367 (297–442)^†	377 (318–430)^‡	323 (251–394)	<0.001
Cardiopulmonary exercise duration, min, N=2044	12 (9–14)	10 (7–12)^†, ^§	9 (7–11)^‡	8 (6–10)	<0.001
Borg rating at peak exercise, N=1998	17 (15–18)	17 (15–19)^§, ^‖	17 (15–19)^¶	17 (15–19)	<0.001
V_E/VCO₂	28 (26–31)	28 (26–31)	38 (35–43)	39 (35–46)	N/A
Peak VO₂, mL/kg per min, N=2061	17 (14–20)	15 (13–19)^†, ^#	13 (11–16)^‡	12 (10–15)	<0.001
Oxygen uptake efficiency slope, N=2053	2.0 (1.6–2.4)	2.0 (1.6–2.4)^#	1.3 (1.0–1.6)	1.3 (1.0–1.7)	<0.001
VO₂ at the ventilatory threshold, mL/kg per min, N=1771	12 (10–14)	11 (9–13)^†, ^#	10 (9–12)^¶	10 (8–11)	<0.001

Values are presented as median (interquartile range) for continuous variables and number (percent) for categorical variables. Because of missing data, N is listed for those variables where the cohort with available data was less than N=2062. KCCQ‐CS indicates Kansas City Cardiomyopathy Questionnaire Clinical Summary score; V_E/VCO₂, minute ventilation/carbon dioxide production; and VO₂, oxygen uptake.

P for comparison among all 4 groups.

^{^†}

P<0.001 vs concordant–lower severity group.

^{^‡}

P<0.001 vs concordant–higher severity group.

^{^§}

P<0.05 vs symptom minimizer group.

^{^‖}

P<0.05 vs concordant–lower severity group.

^{^¶}

P<0.05 vs concordant–higher severity group.

^{^#}

P<0.001 vs symptom minimizer group.