Table 1.
Full cohort (N = 163) |
Firefighters (N = 84) |
Office Workers (N = 79) |
Full cohort | Fire- fighters |
Office workers | |||
---|---|---|---|---|---|---|---|---|
Mean (SD) or GM (GSD)a | Mean (SD) or GM (GSD)a | Mean (SD) or GM (GSD)a | p-valueb | LODc | DFd(%) | DF(%) | DF(%) | |
Age (years) | ||||||||
47.93 (8.10) | 47.38 (4.58) | 48.52 (10.64) | 0.23 | – | – | – | – | |
Dairy consumption (times per week) | ||||||||
14.45 (8.19) | 13.98 (7.30) | 14.96 (9.07) | 0.47 | – | – | – | – | |
Egg consumption (times per week) | ||||||||
3.71 (1.93) | 3.96 (2.00) | 3.46 (1.84) | 0.23 | – | – | – | – | |
Telomere Length (mean TRF in kbpe) | ||||||||
7.90 (1.12) | 8.10 (1.09) | 7.68 (1.13) | 0.01* | – | – | – | – | |
PFAS (ng/mL) | ||||||||
PFHxS | 3.68 (2.79) | 4.55 (2.82) | 2.94 (2.64) | 0.01* | 0.02 | 100 | 100 | 100 |
PFOA | 1.16 (1.76) | 1.13 (1.70) | 1.19 (1.83) | 0.44 | 0.02 | 100 | 100 | 100 |
PFOS | 4.18 (2.08) | 4.33 (1.83) | 4.03 (2.35) | 0.39 | 0.02 | 100 | 100 | 100 |
PFNA | 0.69 (1.94) | 0.77 (1.98) | 0.61 (1.87) | 0.09 | 0.05 | 100 | 100 | 100 |
PFDA | 0.26 (2.09) | 0.27 (1.77) | 0.24 (2.42) | 0.31 | 0.02 | 99 | 100 | 98 |
PFUnDA | 0.18 (4.44) | 0.23 (3.67) | 0.14 (5.19) | 0.06 | 0.02 | 80 | 87 | 73 |
PFBuS | 0.13 (4.28) | 0.13 (4.19) | 0.13 (4.42) | 0.85 | 0.02 | 73 | 74 | 72 |
OPFRs (ng/mL) | ||||||||
BDCPP | 1.92 (5.11) | 4.05 (4.59) | 0.87 (3.85) | ≤0.01* | 0.20 | 95 | 100 | 90 |
BCEP | 0.40 (6.11) | 0.87 (5.72) | --f | --g | 0.10 | 60 | 79 | 39 |
DBuP | 0.20 (3.92) | 0.41 (3.95) | --f | --g | 0.10 | 56 | 82 | 28 |
TBBPA | --f | --f | --f | --g | 0.20 | 44 | 46 | 41 |
DpCP | --f | --f | --f | --g | 0.10 | 29 | 42 | 16 |
a Geometric mean (GM) and geometric standard deviation (GSD) computed for egg consumption, all PFAS, and all OPFRs due to skewed distributions
b p-values derived from Wilcoxon rank-sum tests
c LOD = limit of detection
d DF = detection frequency
e kilobase pairs
f GMs were not calculated for chemicals with detection frequencies below 50%
g Wilcoxon rank-sum tests were not performed for chemicals with detection frequencies below 50% in any group
h All summary statistics calculated using LOD/sqrt [2] for those chemicals with less than 100% detection frequency