Table 2.
Estimated base pair change in telomere length for a doubling of PFAS concentration
| Full Cohort Δbpc (CId) | Firefighters Δbp (CI) | Office Workers Δbp (CI) | |
|---|---|---|---|
| PFHxS | |||
| Model 1a | 103 (−16,223) | 72 (−92,235) | 88 (−98,275) |
| Model 2b | 84 (− 35,202) | 91 (−69,252) | 69 (−116,254) |
| PFOA | |||
| Model 1 | 273 (54,493)* | 395 (85,705)* | 175 (−135,485) |
| Model 2 | 240 (25,455)* | 329 (13,645)* | 165 (−140,470) |
| PFOS | |||
| Model 1 | 183 (15,352)* | 304 (33,576)* | 91 (− 125,308) |
| Model 2 | 172 (5340)* | 272 (− 4548) | 124 (−95,342) |
| PFNA | |||
| Model 1 | 126 (−60,312) | 103 (− 144,350) | 65 (− 233,362) |
| Model 2 | 68 (−117,253) | 52 (−195,299) | 116 (−183,416) |
| PFDA | |||
| Model 1 | 137 (−27,302) | 300 (16,585)* | 34 (−170,239) |
| Model 2 | 104 (−58,266) | 255 (−31,541) | 60 (−148,267) |
| PFUnDA | |||
| Model 1 | 26 (−55,106) | 79 (−50,209) | −31 (−136,75) |
| Model 2 | 13 (−67,93) | 61 (−67,190) | 2 (−114,117) |
| PFBuS | |||
| Model 1 | 10 (−72,92) | −33 (− 151,84) | 50 (−67,168) |
| Model 2 | 23 (−58,104) | −4 (−123,114) | 46 (− 72,165) |
a Model 1 adjusted for age (years)
b Model 2 adjusted for age (years), dairy and egg consumption (times per week), and occupation (in full group only)
c change in base pairs
d CI = 95% confidence interval
* statistically significant (p ≤ 0.05)