Table 1. An overview of the different categories of drugs that are administered as ocular drops for maintaining IOP levels by the clinicians.

Category	Example	Mode of Action	Observations
Cholinergic drugs	Pilocarpene	Increase TM outflow by causing the ciliary muscles to contract	Effective but causes side effects like dim vision
α-adrenergic receptor agonists	Brimonidine	Decrease AH production, and increase outflow via uveal sclera route	Allergic reaction is prominent
β-Adrenergic receptor antagonists (β-blockers)	Levobunolol, Timonol	Reduce AH inflow, by inhibiting its production in the ciliary body	Rare systemic effects such as bradycardia and fatigue
Prostaglandin analogs	Latanoprost, Tafluprost, Bimatoprost	Causes ECM morphogenesis via action of MMP’s, increases outflow facility via uveal sclera pathway	First choice of clinicians, least side effects
Carbonic anhydrase inhibitors	Brinzolamide, Dorzolamide	Decrease AH production	Oral administration is more efficient butcauses side effects such as paresthesia of the hands and feet