Table 3.

Evolution of the Rate of Improvement and of the Prevalence of Improvement in the Overall Unpleasantness Score

Comparison Day 0–Day 2 (N=340)
	Day 0	Day 2
Mean [SD]	5.99 [2.89]	3.14 [2.97]***
Rate of improvement		47.66%
Prevalence of improvement		83.2% [IC: 79.26; 87.21]
Comparison Day 0–Day 14 (N=337)
	Day 0	Day 14
Mean [SD]	6.00 [2.88]	2.53 [2.47]***
Rate of improvement		57.88%
Prevalence of improvement		87.54% [IC: 84.01; 91.06]
Comparison Day 0–Day 28 (N=400)
	Day 0	Day 28
Mean [SD]	6.14 [2.91]	2.29 [2.40]***
Rate of improvement		62.68%
Prevalence of improvement		90% [IC: 87.06; 92.94]

Note: ***p<0.001.

Abbreviation: SD, standard deviation.