Table 4.

protective effect of licorice extract on MTX-induced testicular oxidative stress.

	MDA (nmol/g testicular tissue)	Catalase (U/g testicular tissue)
Control	8.1± 0.3	17.1 ± 1.3
Licorice	7.8 ± 0.21	15 ± 1.3
Methotrexate	28.1 ± 1.9*	6.3 ± 1.5*
Licorice + methotrexate	14.2 ± 1.7**	13.5 ± 1.4**

Values are means ± standard error (SEM) of seven different mice per each treatment. Values are statistically significant at ^*P < 0.05 versus control licorice groups, and ^**P < 0.05 versus methotrexate group.