Table 2.
Unadjusted1 | Adjusted2 | |||||||
---|---|---|---|---|---|---|---|---|
OR | 95% CI | p-value | OR | 95% CI | p-value | |||
Pulmonary exacerbations | ||||||||
Cessation: Intercept | 0.79 | 0.71 | 0.87 | <0.001 | 0.83 | 0.75 | 0.91 | <0.001 |
Cessation: Slope | 0.94 | 0.90 | 0.97 | 0.001 | 0.94 | 0.91 | 0.98 | 0.003 |
β | β | |||||||
ppFEV1 | ||||||||
Cessation: Intercept | 0.73 | 0.37 | 1.08 | <0.001 | 0.69 | 0.34 | 1.04 | <0.001 |
Cessation: Slope | 0.38 | 0.15 | 0.62 | 0.001 | 0.39 | 0.16 | 0.61 | 0.001 |
BMI percentile | ||||||||
Cessation: Intercept | 1.00 | 0.53 | 1.46 | <0.001 | 1.03 | 0.57 | 1.50 | <0.001 |
Cessation: Slope | 0.41 | 0.09 | 0.73 | 0.013 | 0.42 | 0.10 | 0.74 | 0.009 |
Includes time for all three outcomes and a quadratic of time for ppFEV1 and BMI percentile.
Adjusted for age at entry, sex, race/ethnicity, household size, income, father's education, health insurance, genotype, newborn screening, CFTR modulator use, P.aeruginosa, and B. cepacia; includes the quadratic for time.
Note: Changes in the intercept and slope correspond to changes in the first year of cessation and each additional year of cessation, respectively.