Table 4.
Association between types of stroke and urinary cadmium concentration (creatinine standardized).
U-Cd | Cases n | Urinary Cd Median | Adjusted HR (95% CI)a | Urinary Cd Median | Cases n | Adjusted HR (95% CI) a |
---|---|---|---|---|---|---|
Ischemic stroke | Hemorrhagic stroke | |||||
Continuous* | 445 | 1.02 (0.92-1.14) | 0.290 | 89 | 1.04 (0.86-1.26) | |
Quartile 1 | 101 | 0.098 | Ref | 0.094 | 17 | Ref |
Quartile 2 | 104 | 0.166 | 0.95 (0.69-1.33) | 0.167 | 28 | 1.55 (0.82-2.91) |
Quartile 3 | 116 | 0.250 | 1.12 (0.80-1.56) | 0.256 | 20 | 1.07 (0.54-2.13) |
Quartile 4 | 123 | 0.436 | 1.12 (0.78-1.62) | 0.454 | 24 | 1.09 (0.53-2.24) |
Per IQR (0.19, calculated among all 1200 subcohort members)
Fully adjusted model with age as time axis and adjusted for gender, BMI (continuous), education (categorical), and cotinine (continuous).