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. 2021 Aug 30;100:108095. doi: 10.1016/j.intimp.2021.108095

Table 1.

Characteristics of anti-SARS-CoV-2 serological assays: target antigen, method, immunoglobulin class detected, cut-off value in arbitrary units (AU/mL), BAU conversion factor, cut-off value in BAU/mL and dynamic range.

MANUFACTURER KIT ASSAY TARGET ANTIGEN METHOD IMMUNOGLOBULIN DETECTED CUT-OFF (AU/mL) CONVERSION FACTOR
(BAU/mL)
CUT-OFF (BAU/mL) DYNAMIC RANGE*
(BAU/mL)
Mindray SARS-CoV-2
S-RBD IgG
S-RBD CLIA IgG 10 1.216 12.16 3.65–1216
Roche Elecsys S-RBD ECLIA IgA, IgM, IgG 0.80 1.288 0.823 0.40–243
anti-SARS-CoV-2 S
Snibe Maglumi S-RBD CLIA IgG 1 4.33 4.33 0.78–433
SARS-CoV-2
S-RBD IgG
DiaSorin LIAISON
SARS CoV-2
Trimeric S CLIA IgG 13 2.6 33.8 4.8–2080
Trimeric S IgG
Thermo Fisher EliA SARS-CoV-2-Sp1 IgG S1 FEIA IgG 7
(7–10 borderline)
4 28
(28–40 borderline)
2.8–816
Euroimmun Anti-SARS-CoV-2 S1 ELISA IgG 8
(8–11 borderline)
3.2 25.6
(25.6–35.2 borderline)
3.2–384
QuantiVac ELISA IgG

CLIA, chemiluminescence immunoassay; ECLIA, electrochemiluminescence immunoassay; ELISA, enzyme-linked immunosorbent assay; FEIA, fluorescence enzyme immunoassay.