Table 2.

Relationship between each variable and the development of grade 3 oral mucositis.

Factor		Cox proportional hazard model			Logistic regression
		p-value	HR	95% CI	p-value	OR	95% CI
Age		0.333			0.136
Sex	Male vs. female	0.164			0.093
Body mass index (BMI)		0.377			0.106
Diabetes	(−) vs. (+)	0.193			0.246
Hemoglobin		∗0.012	0.833	0.723–0.961	∗0.013	0.755	0.606–0.942
Leukocyte		0.634			0.670
Lymphocyte		0.408			0.519
Albumin		0.425			0.105
Creatinine		0.334			0.255
Concurrent therapy	RT alone vs. RT + cisplatin vs. RT + cetuximab	∗0.010	1.802	1.152–2.819	∗0.006	2.237	1.266–3.954
Radiation method	3D-CRT vs. IMRT	0.945			0.572
Total dose		0.449			0.432
Use of spacer	(−) vs. (+)	0.963			0.309
Pilocarpine hydrochloride	(−) vs. (+)	0.115			∗0.047	0.369	0.138–0.986
Corticosteroid ointment	(−) vs. (+)	0.875			0.560
Number of teeth		∗0.042	1.03	1.001–1.060	0.097
Number of metal teeth		0.957			0.271
Alveolar bone loss	<1/2 vs. ≥1/2	0.809			0.597

RT: radiotherapy, 3D-CRT: three-dimensional conformal radiation therapy, IMRT: intensity modulated radiation therapy, HR: hazard ratio, CI: confidence interval.

∗p < 0.05.