Table 4.
Odds ratios (ORs) for respiratory and cardiovascular disease in two multivariable models with FEV1.
| Respiratory disease | Cardiovascular disease | ||||||
|---|---|---|---|---|---|---|---|
| OR (95%CI) | p | OR (95%CI) | p | ||||
| Age (per 10-year increase) | 1•21 (1•11, 1•33) | <0•01 | 1•57 (1•41, 1•76) | <0•01 | |||
| Sex | Female | 0•99 (0•77, 1•28) | 0•95 | 0•69 (0•54, 0•89) | <0•01 | ||
| First Nations status | 1•87 (0•96, 3•66) | 0•07 | 0•98 (0•35, 2•77) | 0•59 | |||
| BMI | Underweight | 0•99 (0•54, 1•82) | 0•42 | 1•01 (0•53, 1•91) | 0•15 | ||
| Normal | Reference | Reference | |||||
| Overweight | 1•10 (0•76, 1•59) | 1•45 (0•98, 2•15) | |||||
| Obese | 1•29 (0•93, 1•80) | 1•07 (0•74, 1•55) | |||||
| Smoking*(n=1571) | Current | 1•07 (0•76, 1•50) | 0•27 | 1•71 (1•17, 2•50) | 0•02 | ||
| Former | 1•31 (0•92, 1•86) | 1•52 (1•06, 2•19) | |||||
| Never | Reference | Reference | |||||
| FEV1 | Z-score | ||||||
| Clinically normal | ≥0 | Reference | <0•01 | Reference | 0•02 | ||
| <0 to -1 | 1•64 (0•87, 3•12) | 1•29 (0•53, 3•15) | |||||
| <-1 to -2 | 2•79 (1•46, 5•33) | 1•07 (0•46, 2•48) | |||||
| Clinically abnormal | <-2 | 6•02 (3•17, 11•42) | 2•15 (0•98, 4•71) | ||||
| Hypertension | 1•26 (0•93, 1•71) | 0•14 | 2•15 (1•63, 2•83) | <0•01 | |||
| Type 2 diabetes | 0•95 (0•69, 1•33) | 0•78 | 2•44 (1•82, 3•27) | <0•01 | |||
*Patients with missing smoking data (n=163) included in modelling but excluded from global Wald test.