Table 5.
Odds ratios (ORs) for respiratory and cardiovascular disease in two multivariable models with FVC.
| Respiratory disease | Cardiovascular disease | ||||||
|---|---|---|---|---|---|---|---|
| OR (95%CI) | p | OR (95%CI) | p | ||||
| Age (per 10-year increase) | 1•25 (1•14, 1•36) | <0•01 | 1•61 (1•44, 1•80) | <0•01 | |||
| Sex | Female | 1•06 (0•58, 1•92) | 0•85 | 0•68 (0•53, 0•88) | <0•01 | ||
| First Nations status | 1•52 (0•85, 2•70) | 0•16 | 0•71 (0•31, 1•59) | 0•40 | |||
| BMI | Underweight | 1•06 (0•58, 1•92) | 0•61 | 0•97 (0•49, 1•90) | 0•11 | ||
| Normal | Reference | Reference | |||||
| Overweight | 1•07 (0•74, 1•54) | 1•45 (0•98, 2•14) | |||||
| Obese | 1•23 (0•89, 1•70) | 1•03 (0•71, 1•49) | |||||
| Smoking*(n=1571) | Current | 1•21 (0•87, 1•68) | 0•11 | 1•77 (1•22, 2•58) | <0•01 | ||
| Former | 1•45 (1•02, 2•06) | 1•55 (1•08, 2•22) | |||||
| Never | Reference | Reference | |||||
| FVC | Z-score | ||||||
| Clinically normal | ≥0 | Reference | <0•01 | Reference | <0•01 | ||
| <0 to -1 | 1•64 (0•92, 2•90) | 0•81 (0•38, 1•74) | |||||
| <-1 to -2 | 2•07 (1•15, 3•73) | 1•09 (0•52, 2•28) | |||||
| Clinically abnormal | <-2 | 3•61 (1•89, 6•88) | 2•18 (1•07, 4•44) | ||||
| Hypertension | 1•29 (0•96, 1•75) | 0•09 | 2•19 (1•66, 2•88) | <0•01 | |||
| Type 2 diabetes | 0•92 (0•66, 1•28) | 0•62 | 2•26 (1•68, 3•03) | <0•01 | |||
*Patients with missing smoking data (n=163) included in modelling but excluded from global Wald test.