FIGURE 2.

We identified 4 families of sequence‐similar fold switchers: transcription repressors XFaso 1/XPH2 (A) Transcription/translation factor RfaH (B) signaling protein KaiB (C) binding proteins GA98/GB98 (D). Colored regions of each panel are fold‐switched regions. Gray regions are structurally unchanged between the two conformations. Upper/lower sequences and secondary structures correspond to protein structures on the left/right, respectively. Most sequences were too long to fit on a single line. Lower sets of sequences/secondary structures are a continuation of the sequences/secondary structures above them