TABLE 2.
α<‐>β prediction discrepancies (mean ± SD) for fold switchers (top 3 rows) and single‐fold proteins (bottom 3 rows) a
| JPred4 (%) | PSIPRED (%) | SPIDER3 (%) | |
|---|---|---|---|
| RfaH b | 44 | 4 | 0 |
| Cro | 19 ± 2 | 0 ± 0 | 11 ± 8 |
| KaiB | 0 ± 0 | 0 ± 1 | 0 ± 0 |
| GA/GB | 17 ± 2 | 8 ± 8 | 3 ± 2 |
| SH3‐like c | 0 ± 0 | 4 ± 2 | 0 ± 0 |
| Myoglobin‐like c | 0 ± 0 | 0 ± 0 | 0 ± 0 |
| α/β‐grasp c | 1 ± 2 | 4 ± 2 | 9 ± 6 |
a
Shaded entries exceed the reported error of 6% for homology‐based secondary structure predictors.
b
Error for RfaH could not be determined because only one measurement of α<‐>β prediction discrepancies could be taken.
c
Families of sequence‐similar fold switchers.