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. Author manuscript; available in PMC: 2022 Apr 2.
Published in final edited form as: J Mol Biol. 2021 Feb 2;433(7):166839. doi: 10.1016/j.jmb.2021.166839

Fig. 1. Characteristics of PGBDs in vertebrates.

Fig. 1.

(a) Domain organization in PGBD proteins. For each domesticated sequence, colored boxes represent domains. Yellow is for Zn-SCAN domain, gray is for an unknown domain, red is for CSB domain, light blue is for SCAN domain and green is for zF-FCS. The orange circle is for CRD or CRD-like domains. Blue is for the catalytic triad with the composition of the residues. The catalytic triad is in pink for PGBD5 because it is not aligned with other domesticated sequences. (b) Distribution of PGBDs in vertebrates. Each coloured square represents a PGBD. PGBD1 and PGBD2 are found in mammals, PGBD3 and PGBD4 are found in haplorrhinis, PGBD5 is present in all vertebrates and cephalochordates but not in tunicates. PGBD6 is specific to anura, PGBD7 is found in Afrotheria, PGBD8 is specific to Strepsirrhini and PGBD9 is found in Actinopterygii.