Table 7.

Molecular docking analysis of studied compounds against IMPDH (1NF7).

Ligand No	Ligands	Free Energy of Binding (kcal/mol)	Hydrogen bond	Salt Bridge	Hydrophobic
1	NMN	-8.7	SER68, PRO69, ASN303, ARG322, GLY326, SER327, GLY328, ASP364, GLY365, SER388, TYR411	-	-
2	Favipiravir-RMP	-8.6	SER68, ASP274, SER275, ASN303, GLY328, MET414, GLY415	ARG322	-
3	Mizoribine monophosphate	-8.9	SER68, ASN303, GLY326, SER327, GLY328, SER329, ILE330, ASP364, GLY365, GLY366, ILE367, GLY387, SER388, TYR411	-	-
4	Ribavirin monophosphate	-8.7	SER68, ASN303, ARG322, GLY324, GLY326, SER327, GLY328, SER329, ASP364, GLY366, SER388, TYR411	-	-