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. 2021 Jul 24;9(8):e1747. doi: 10.1002/mgg3.1747

TABLE 9.

Association between IRS1 rs2943656 genotypes (AA, AG, & GG) and body composition and anthropometric indices

Male Genotype (n) F p Female Genotype (n) F p
Index AA (4) AG (23) GG (53) Index AA (2) AG (29) GG (49)
Age 53.25 ± 7.46 50.48 ± 6.81 53.40 ± 7.58 1.278 0.284 Age 55.00 ± 14.14 52.79 ± 7.82 54.39 ± 8.63 0.345 0.709
Height (cm) 167.75 ± 3.50 170.37 ± 7.71 167.74 ± 7.00 1.125 0.330 Height (cm) 154.50 ± 3.54 159.19 ± 4.49 157.74 ± 5.89 1.133 0.328
Weight (kg) 72.83 ± 14.58 63.24 ± 10.21 63.45 ± 9.96 1.614 0.206 Weight (kg) 59.70 ± 20.51 62.56 ± 10.99 58.16 ± 10.33 1.524 0.224
BMI (kg/m2) 25.95 ± 5.36 21.76 ± 3.09 22.52 ± 3.10 2.911 0.060 BMI (kg/m2) 24.80 ± 7.50 24.64 ± 3.97 23.31 ± 3.74 1.127 0.329
FFM (kg) 53.83 ± 3.82 50.15 ± 6.30 50.49 ± 6.09 0.632 0.535 FFM (kg) 37.95 ± 5.87 40.58 ± 4.04 39.40 ± 3.83 1.040 0.358
FM (kg) 19.03 ± 11.05 13.13 ± 4.81 12.99 ± 5.16 2.328 0.104 FM (kg) 21.80 ± 14.71 22.00 ± 7.65 18.78 ± 7.55 1.640 0.201
SMM (kg) 51.05 ± 3.65 47.53 ± 5.98 47.86 ± 5.79 0.641 0.530 SMM (kg) 35.80 ± 5.37 38.19 ± 3.71 37.11 ± 3.50 1.028 0.363
TSM (kg) 28.30 ± 0.48 26.58 ± 2.96 26.84 ± 2.92 0.608 0.547 TSM (kg) 20.50 ± 1.13 21.98 ± 1.69 21.81 ± 1.94 0.614 0.544
LUSM (kg) 2.80 ± 0.26 2.53 ± 0.41 2.57 ± 0.38 0.850 0.431 LUSM (kg) 1.85 ± 0.49 1.92 ± 0.31 1.81 ± 0.24 1.465 0.237
LLSM (kg) 8.53 ± 1.45 7.90 ± 1.21 7.88 ± 1.17 0.550 0.579 LLSM (kg) 5.65 ± 1.63 6.09 ± 0.86 5.80 ± 0.67 1.443 0.243
RUSM (kg) 2.85 ± 0.30 2.61 ± 0.41 2.67 ± 0.39 0.650 0.525 RUSM (kg) 1.95 ± 0.49 2.01 ± 0.33 1.90 ± 0.26 1.478 0.234
RLSM (kg) 8.68 ± 1.54 8.01 ± 1.33 8.02 ± 1.16 0.540 0.585 RLSM (kg) 5.90 ± 1.56 6.28 ± 0.80 5.90 ± 0.68 2.408 0.097
TFM (kg) 11.23 ± 6.80 7.64 ± 2.97 7.54 ± 3.29 2.187 0.119 TFM (kg) 12.15 ± 8.56 12.46 ± 4.79 10.63 ± 5.02 1.247 0.293
LUFM (kg) 0.73 ± 0.50 0.47 ± 0.20 0.47 ± 0.22 2.247 0.113 LUFM (kg) 1.10 ± 0.99 1.02 ± 0.49 0.80 ± 0.44 2.187 0.119
LLFM (kg) 3.28 ± 1.68 2.33 ± 0.76 2.32 ± 0.76 2.590 0.082 LLFM (kg) 3.75 ± 2.05 3.78 ± 0.98 3.30 ± 0.85 2.471 0.091
RUFM (kg) 0.70 ± 0.45 0.47 ± 0.19 0.45 ± 0.19 2.665 0.076 RUFM (kg) 1.05 ± 0.92 1.00 ± 0.50 0.78 ± 0.44 1.980 0.145
RLFM (kg) 3.28 ± 1.68 2.33 ± 0.75 2.30 ± 0.78 2.592 0.081 RLFM (kg) 3.90 ± 2.12 3.87 ± 1.00 3.39 ± 0.87 2.411 0.096
HS (kg) 39.68 ± 9.17 30.93 ± 7.74 30.82 ± 7.58 2.499 0.089 HS (kg) 21.55 ± 9.55 19.89 ± 7.60 19.13 ± 5.49 0.238 0.788

Abbreviations: BMI, body mass index; FFM, fat‐free mass; FM, fat mass; HS, handgrip strength; LLFM, left lower limb fat mass; LLSM, left lower limb skeletal muscle mass; LUFM, left upper limb fat mass; LUSM, left upper limb skeletal muscle mass; RLFM, right lower limb fat mass; RLSM, right lower limb skeletal muscle mass; RUFM, right upper limb fat mass; RUSM, right upper limb skeletal muscle mass; SMM, skeletal muscle mass; TFM, trunk fat mass; TSM, trunk skeletal muscle mass.