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. 2021 Aug 30;21:460. doi: 10.1186/s12935-021-02154-w

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Cell types identification and dynamic expression of ATG genes in human fetal kidney. a UMPA plot of single cells mapped in this work differently colored by 16 main cell types. b Cell number of each main cell type fractioned by embryo weeks with different color annotations. c Overview for cell cycle scores (G1, G2M, S) of single cells clustered by cell types and embryo weeks with different color annotations. d Top 5 gene markers of 16 main cell types identified in this atlas. The bubble size presented the expressed percent, and the bubble color presented the average expression level of each gene. e Expressed ATG genes per single cell ranging from 9 to 18 weeks of four human fetal kidney. Blue line presents mean number of expressed ATG-genes in each cell; Orange bar presents mean ATG-genes expression per cell [log2(TPM + 1)]