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Multivariate analysis by the Cox proportional hazard regression model for OS in younger GBM patients (age < 60 yrs) of TCGA database
| Variable | HR (95% CI) | P |
|---|---|---|
| Gender | ||
| Male vs female | 2.029 (1.286–3.201) | 0.002 |
| LANCL2 gene status | ||
| Amplification vs no alteration | 1.657 (1.017–2.699) | 0.043 |
| EGFR gene status | ||
| Amplification vs no alteration | NA | 0.624 |
| LANCL2 and EGFR gene status | ||
| Co-amplification vs no alteration | NA | NA |
HR hazard ratio, CI confidence interval, NA not applicable
