Database	Time span	Search strategy
The Cochrane Hepato‐Biliary Group Controlled Trials Register	Date will be given at review stage	(vasoactiv* or vasoconstrict* or vasodilat* or vasopress* or inotrop* or terlipressin* or somatostatin* or octreotid* or noradrenalin* or norepinephrin* or midodrin*) and (paracentes* or drain* or punctur* or centes*) and (cirrho* or fibro* or ascit*)
Cochrane Central Register of Controlled Trials (CENTRAL)	Latest issue	#1 MeSH descriptor: [Vasoconstrictor Agents] explode all trees #2 MeSH descriptor: [Vasodilator Agents] explode all trees #3 MeSH descriptor: [Vasopressins] explode all trees #4 MeSH descriptor: [Somatostatin] explode all trees #5 MeSH descriptor: [Octreotide] explode all trees #6 MeSH descriptor: [Norepinephrine] explode all trees #7 MeSH descriptor: [Midodrine] explode all trees #8 (vasoactiv* or vasoconstrict* or vasodilat* or vasopress* or inotrop* or terlipressin* or somatostatin* or octreotid* or noradrenalin* or norepinephrin* or midodrin*) #9 #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 #10 MeSH descriptor: [Paracentesis] explode all trees #11 (paracentes* or drain* or punctur* or centes*) #12 #10 or #11 #13 MeSH descriptor: [Fibrosis] explode all trees #14 MeSH descriptor: [Liver Cirrhosis] explode all trees #15 MeSH descriptor: [Ascites] explode all trees #16 (cirrho* or fibro* or ascit*) #17 #13 or #14 or #15 or #16 #18 #9 and #12 and #17
MEDLINE Ovid	1946 to the date of the search	1. exp vasoconstrictor agents/ or exp vasodilator agents/ 2. exp Vasopressins/ 3. exp Somatostatin/ 4. exp Octreotide/ 5. exp Norepinephrine/ 6. exp Midodrine/ 7. (vasoactiv* or vasoconstrict* or vasodilat* or vasopress* or inotrop* or terlipressin* or somatostatin* or octreotid* or noradrenalin* or norepinephrin* or midodrin*).mp. [mp=title, abstract, original title, name of substance word, subject heading word, floating sub‐heading word, keyword heading word, organism supplementary concept word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms] 8. 1 or 2 or 3 or 4 or 5 or 6 or 7 9. exp Paracentesis/ 10. (paracentes* or drain* or punctur* or centes*).mp. [mp=title, abstract, original title, name of substance word, subject heading word, floating sub‐heading word, keyword heading word, organism supplementary concept word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms] 11. 9 or 10 12. exp Fibrosis/ 13. exp Liver Cirrhosis/ 14. exp Ascites/ 15. (cirrho* or fibro* or ascit*).mp. [mp=title, abstract, original title, name of substance word, subject heading word, floating sub‐heading word, keyword heading word, organism supplementary concept word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms] 16. 12 or 13 or 14 or 15 17. 8 and 11 and 16
Embase Ovid	1974 to the date of the  search	1. exp vasoactive agent/ 2. exp inotropic agent/ 3. exp vasopressin/ 4. exp terlipressin/ 5. exp somatostatin/ 6. exp octreotide/ 7. exp noradrenalin/ 8. midodrine/ 9. (vasoactiv* or vasoconstrict* or vasodilat* or vasopress* or inotrop* or terlipressin* or somatostatin* or octreotid* or noradrenalin* or norepinephrin* or midodrin*).mp. [mp=title, abstract, heading word, drug trade name, original title, device manufacturer, drug manufacturer, device trade name, keyword, floating subheading word, candidate term word] 10. 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 or 9 11. exp paracentesis/ 12. (paracentes* or drain* or punctur* or centes*).mp. [mp=title, abstract, heading word, drug trade name, original title, device manufacturer, drug manufacturer, device trade name, keyword, floating subheading word, candidate term word] 13. 11 or 12 14. exp liver cirrhosis/ 15. exp liver fibrosis/ 16. exp ascites/ 17. (cirrho* or fibro* or ascit*).mp. [mp=title, abstract, heading word, drug trade name, original title, device manufacturer, drug manufacturer, device trade name, keyword, floating subheading word, candidate term word] 18. 14 or 15 or 16 or 17 19. 10 and 13 and 18 20. Randomized controlled trial/ or Controlled clinical trial/ or trial.ti. 21. (random* or blind* or placebo* or meta‐analys*).mp. [mp=title, abstract, heading word, drug trade name, original title, device manufacturer, drug manufacturer, device trade name, keyword, floating subheading word, candidate term word] 22. 19 and (20 or 21)
LILACS (Bireme)	1982 to the date of the search	(vasoactiv$ or vasoconstrict$ or vasodilat$ or vasopress$ or inotrop$ or terlipressin$ or somatostatin$ or octreotid$ or noradrenalin$ or norepinephrin$ or midodrin$) [Words] and (paracentes$ or drain$ or punctur$ or centes$) [Words] and (cirrho$ or fibro$ or ascit$) [Words]
Science Citation Index Expanded (Web of Science)	1900 to the date of the search	#4 #3 AND #2 AND #1 #3 TS=(cirrho* or fibro* or ascit*) #2 TS=(paracentes* or drain* or punctur* or centes*) #1 TS=(vasoactiv* or vasoconstrict* or vasodilat* or vasopress* or inotrop* or terlipressin* or somatostatin* or octreotid* or noradrenalin* or norepinephrin* or midodrin*)
Conference Proceedings Citation Index‐Science (Web of Science)	1990 to the date of the search	#4 #3 AND #2 AND #1 #3 TS=(cirrho* or fibro* or ascit*) #2 TS=(paracentes* or drain* or punctur* or centes*) #1 TS=(vasoactiv* or vasoconstrict* or vasodilat* or vasopress* or inotrop* or terlipressin* or somatostatin* or octreotid* or noradrenalin* or norepinephrin* or midodrin*)