Table 2.

Panoramic features of exposed MRONJ

Author	Study design	Sample size	Imaging features
Şahin et al.42	A case–control study	38 exposed MRONJ	Diffused and focal sclerosis25,42,43,47
		28 non-exposed MRONJ	Mixed osteolysis and sclerosis43–45
Klingelhöffer et al.47	A case–control study	36 MRONJ patients	Prominent mandibular canal42,43,47
	(randomized, examiner-blinded)	24 medicated non-MRONJ	Sequestrum formation42,46
		60 controls	Visible extraction socket46,47
Shin et al.46	Comparative case series	161 medication-related patients 203 medication-unrelated patients	Lamina dura thickening47; insignificant in another study45
			Periosteal reaction47
Suei45	Comparative case series	25 patients	Cortex disruption47
Marx et al.44	Retrospective case series	119 patients
Phal et al.25	Retrospective case series	15 patients
Cardoso et al.43	Retrospective case series	35 patients
Ruggiero et al.5	Position paper		Stage 1 and 2 – limited to alveolar bone
			Stage 3 – beyond alveolar bone area

MRONJ, medication-related osteonecrosis of the jaw.