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. 2021 Jan 15;50(6):20200417. doi: 10.1259/dmfr.20200417

Table 6.

Potential indicators from functional imaging

Author Study design Sample size Imaging features
Watanabe et al.113 Retrospective case series 44 patients
  • BSIJmax with cut-off points of 0.09 in maxilla, 0.06 in mandible

Fleisher et al.114 Retrospective case series 23 patients
  • SUVmax = 6.59 (standard deviation not available)

Watanabe et al.110 Retrospective case series 12 patients
  • SUVmax = 6.4±2.1

Raje et al.68 Retrospective case series 10 patients
  • SUVmax = 7.5±2.9

Catalano et al.115 Retrospective case series 4 patients
  • FDG-PET positive, Tc-99m-sestamibi negative indicate MRONJ

Subramanian et al.111 Case reports 2 patients
  • FI/CBCT features of MRONJ outline

  • Include necrotic area (FDG-PET/ SPECT negative)

  • Include current inflammation (FDG-PET positive)

  • Exclude vital and reactive area (SPECT, NAF-PET positive)

CBCT, cone beam CT; FDG, flurodeoxyglucose; FI, functional imaging ; MRONJ, medication-related osteonecrosis of the jaw; PET, positron emission tomography; SPECT, single photon emission tomography; SUVmax, maximum standardized uptake value.