Figure 2.

Metoprolol Rescues Pulmonary Function in ICU Patients With Severe COVID-19

(A and B) Improved oxygenation (PaO₂ and PaO₂:FiO₂) in patients receiving metoprolol, but not those in the control group. Data are presented as individuals’ (dots) paired data between days 1 and 4. ∗P < 0.05, ∗∗P < 0.01 by paired Student's t-test. (C) Days spent by severe COVID-19 patients on IMV and in the ICU according to allocation to IV metoprolol or control (no treatment). Control, n = 8; metoprolol, n = 12. FiO₂ = fraction of inspired oxygen; ICU = intensive care unit; IMV = invasive mechanical ventilation; PAFI = PaO₂:FiO₂ ratio; other abbreviations as in Figure 1.