Table 2.
Baseline and Post-Treatment Ventilation Parameters
| Baseline |
Day 4 |
|||||
|---|---|---|---|---|---|---|
| Metoprolol | Control | P Value | Metoprolol | Control | P Value | |
| PaO2, mm Hg | 87.5 (78.8, 110.0) | 104.0 (93.0, 122) | 0.105 | 108.0 (98.3, 139.0) | 83.5 (77.3, 92.5) | 0.004 |
| PaCO2, mm Hg | 48.5 (43.8, 52.5) | 47 (41.5, 48.8) | 0.562 | 51.0 (46.5, 53.3) | 47.0 (45.3, 50.5) | 0.353 |
| PEEP, cm H2O | 12.0 (10.0, 12.5) | 13.0 (10.0, 14.0) | 0.625 | 10.0 (9.00, 12.0) | 11.0 (10.0, 12.0) | 0.666 |
| FiO2 | 0.60 (0.5, 0.75) | 0.48 (0.44, 0.60) | 0.241 | 0.40 (0.39, 0.53) | 0.43 (0.40, 0.57) | 0.634 |
| PaO2/FiO2, | 130 (110, 162) | 223 (188, 242) | 0.076 | 267 (199, 298) | 163 (145, 209) | 0.037 |
| Lactic acid, mmol/L | 1.3 (1.2, 1.8) | 1.2 (0.98, 2.00) | 0.785 | 1.4 (1.20, 1.73) | 1.9 (1.50, 2.05) | 0.094 |
| pH | 7.41 (7.38, 7.42) | 7.42 (7.37, 7.45) | 0.485 | 7.43 (7.40, 7.46) | 7.41 (7.38, 7.44) | 0.461 |
Values are median (Q1, Q3). Bold indicates statistical significance.
FiO2 = fraction of inspired oxygen; PaCO2 = partial pressure of carbon dioxide; PaO2 = partial pressure of oxygen; PEEP = positive end-expiratory pressure.