Figure 3.

Relative hepatic expression of the PPARα target gene cytochrome acyl CoA oxidase (Acox1) in wild-type (Ppara^+/+), Ppara-null (Ppara^–/–), or PPARA-humanized (PPARA) mice after either 1 week, 5 weeks, 26 weeks, or long-term administration of GW7647 administration initiated on postnatal day 3 of neonatal development. Individual mouse data are presented as circles in the scatter plots, with the mean and standard deviation shown by lines within each scatter plot. Groups with different letters are statistically significant from control at p ≤ .05.