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. 2021 Jul 8;183(1):214–226. doi: 10.1093/toxsci/kfab083

Figure 2.

Figure 2.

Bisphenol inhibition of sodium currents. Whole-cell voltage-clamp recordings of fast/peak sodium current (INa-P) following acute (5–10 min) exposure to (A) BPA, (B) BPF, or (C) BPS. D, Dose-dependent inhibition of INa-P (mean ± SD). E, Calculated IC50 values are shown. Whole-cell voltage-clamp recordings of late sodium current (INa-L) following exposure to (F) BPA, (G) BPF, or (H) BPS. I, Dose-dependent inhibition of INa-L (mean ± SD). J, Calculated IC50 values are shown. n = 4 independent cell recordings per study. Abbreviations: BPA, bisphenol A; BPS, bisphenol S; BPF, bisphenol F.