Table 3. Summary of studies performing 20WBCT after antivenom.
First author, year | Reference clotting assay | Time of repeat 20WBCT | Number of 20WBCT | True positive | False negative | True negative | False positive | Sensitivity (Confidence interval) | Specificity (Confidence interval) |
---|---|---|---|---|---|---|---|---|---|
Shenoy, 2020 | INR >1·4 | 6 h | 37 | 5 | 7 | 21 | 4 | 0·42 (0·15–0·72) | 0·84 (0·64–0·95) |
DSilva, 2019 | INR >1·4 | 12 h | 59 | 2 | 1 | 45 | 11 | 0·67 (0·02–0·45) | 0·80 (0·68–0·90) |
Oliveira, 2019 | fibrinogen <100 mg/dL | 12 h | 73 | 2 | 39 | 32 | 0 | 0·05 (0·01–0·17) | 1·00 (0·89–1·00) |
Sano-martins, 1994 | fibrinogen <100 mg/dL | 6 h | 69 | 8 | 34 | 27 | 0 | 0·19 (0·09–0·34) | 1·00 (0·87–1·00) |