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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Nat Chem. 2021 Apr 8;13(6):540–548. doi: 10.1038/s41557-021-00660-y

Figure 5 |. Selections against tumor-associated antigens and human CtIP.

Figure 5 |

Two-dimensional fingerprints of selections against: a, human tenascin-C (hTNC); b, murine tenascin-C (mTNC); c, the L27E mutant of N-terminal CtIP d, urokinase-type plasminogen activator (uPA). A cut-off value equal to 20 was applied to all the fingerprints. The most enriched combinations (A481/B335 for hTNC and mTNC, A110/B453 for uPA and A54/B369 for L27E-CtIP) were re-synthesized off-DNA and validated by small-molecule ELISA. Error bars indicate standard deviation of three measurements. Details on DNA counts for individual library members, enrichment factors and dissociation constants are reported in Supplementary Tables 2,3 and 6. The asterisk (*) indicates the dissociation constant value (Kd).