Fig.4.

Protein expression levels of inflammatory factors (TGF-β, TNF-β, NF-KB, IL-1β, IL-6 and TNF-α) in chondrocytes as determined by Western blot analysis. Control group: chondrocytes cultured in Dulbecco’s Modified Eagle’s Medium (DMEM), IL-1β group: chondrocytes cultured in DMEM with 10 ng/ ml IL-1β for 24 hours followed by exposure to 0 μg/ml exosomes for 48 hours, IL-1β+EXOs group: chondrocytes cultured in DMEM with 10 ng/ml IL-1β for 24 hours and then exposed to 10 μg/ml exosomes for 48 hours. TGF-β; Transforming growth factor-β, TNF-β; Tumor necrosis factor-β, NF-ΚB; Nuclear factor kappa-B, IL-1β; Interleukin-1β, IL-6; Interleukin-6, TNF-α; Tumor necrosis factor-α, and EXOs; Exosomes.