Table 1.
Comparison of the Scoring of Acute Toxicity in RTOG and CTCAE
| RTOG | NCI CTCAE v.5.0 | |
|---|---|---|
| Grade 0 | Normal skin, no visible symptoms | Normal skin, no visible symptoms |
| Grade I | Follicular, faint or dull erythema, Epilation, dry desquamation decreased sweating | Faint erythema, dry desquamation |
| Grade II | Tender or bright erythema, patchy moist desquamation confined to skin folds, moderate edema | Moderate to brisk erythema, patchy moist desquamation confined to the skin folds and creases, moderate edema |
| Grade III | Confluent, moist desquamation in areas other than in the skin folds, pitting edema - bleeding may occur | Moist desquamation in areas other than in the skin folds and creases, bleeding induced by minor trauma or abrasion |
| Grade IV | Ulceration, hemorrhage and necrosis | Skin necrosis or ulceration of full thickness in the dermis, spontaneous bleeding from involved site |
| Grade V | The intensity of the reaction was not determined | Death |