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. 2021 Aug 24;13(1):1961202. doi: 10.1080/19490976.2021.1961202

Table 4.

Murine models that examine the impact of helminth coinfection on sexually transmitted viruses

Virus
Helminth
Helminth target tissue
Timing of virus coinfection Outcome compared to virus-only mice
Mechanism
Reference
Herpes simplex virus-2 Nippostrongylus brasiliensis Lungs, gut Day 7 post helminth infection.
Coinfected mice had vaginal epithelial ulceration. No change in viral load compared to virus-alone.
IL-33/IL-5/eosinophil axis Chetty et al., 202172