Skip to main content
. 2021 Aug 26;13:6721–6730. doi: 10.2147/CMAR.S317627

Table 3.

Utility Score of the Three Key Reference Papers About Cost-Effectiveness Analysis of Active Surveillance versus Early Surgery in Papillary Thyroid Cancer

Key Reference Paper (Year), Country Utility Score
Lang et al (2015), Hong Kong21
 Alive without permanent complication 1
 Alive with permanent complication 0.54
 Death 0
Venkatesh et al (2017), USA22
 Disease-free state after lobectomy without complication 0.99
 Disease-free state after operation and RAI 0.95
 Disease-free state after lobectomy with short-term complication 0.75
 Lobectomy 0.74
 RAI 0.64
 Disease-free state after lobectomy with long-term complication 0.63
 Redo LND 0.56
 TTLND 0.55
 TTLND with complication 0.54
 Disease recurrence 0.54
 Redo LND with complication 0.41
 Disutility difference of AS compared to disease-free state post-lobectomy without complication 0.11
White et al (2020), USA24
 Hypoparathyroidism 0.836
 Hypothyroidism 0.83
 Unilateral RLN injury 0.627
 Cancer recurrence 0.54
 Distant metastatic disease 0.25
 Bilateral RLN injury 0.205
 Diagnosis −0.04a
 FNA biopsy −0.5
 Hematoma during surgery −0.5
 Airway problem during surgery −0.5
 Patient baseline utilities Variable

Notes: aWhite et al24 estimated disutility and summed it into the patient’s total lifetime utility score.

Abbreviations: RLN, recurrent laryngeal nerve; FNA, fine needle aspiration; RAI, radioactive iodine; LND, lymph node dissection; TT, total thyroidectomy.