Table 2.
Feature (sigma) | Observed | erf (x/2) | PI 1 − erf (x/2) | erf (x/2)N | PM 1 − erf (x/2)N | Expected random features in the DED map N × (1 − erf(x/2)) |
---|---|---|---|---|---|---|
1 | >8,000 | 0.68 | 0.31 | 0.0 | 1.0 | 216238 |
2 | >8,000 | 0.95 | 0.05 | 0.0 | 1.0 | 31,007 |
3 | 3,167 | 0.997 | 0.002 | 0.0 | 1.0 | 1,839 |
4 | 1,018 | 1.0 | 0.0 | 0.0 | 1.0 | 43 |
5 | 264 | 1.0 | 0.0 | 0.67 | 0.33 | 0.4 |
6 | 44 | 1.0 | 0.0 | 1.0 | 0.0 | 0.0 |
Random features were estimated as a function of a multiple (x) of sigma (sigma level) in the unit cell of the SaBphP2 difference map calculated on an 88 × 88 × 88 grid (N = 681,472). The number of observed peaks was determined by the ccp4 program peakmax as a function of the DED sigma value. PM is the probability of observing at least one random feature equal to or more than a given sigma level in the entire map, as opposed to the probability PI of observing this random feature in an individual voxel. Note that we write (1 − erf) rather than using the equivalent erfc, where erf is the error function.