Table 2.
EBV+ DLBCL-NOS | ≤50 y | >50 y | P | |
---|---|---|---|---|
First-line therapy, n | 69* | 23 | 46* | |
Intent-to-cure therapy | 56 (81) | 23 (100) | 33 (72) | .003 |
Immunochemotherapy ± RT | 41 (73) | 16 (70) | 25 (76) | .760 |
Chemotherapy ± RT, n (%) | 15 (27) | 7 (30) | 8 (24) | |
ASCT | 3 (4) | 3 (13) | 0 | .03 |
Palliative care | 13 (19) | 0 | 13 (28) | |
Response to first-line intent-to-cure therapy, n | 56 | 23 | 33 | |
CR | 41 (73) | 21 (91) | 20 (61) | .014 |
PD | 10 (18) | 0 | 10 (30) | .003 |
NA (death other cause) | 5 (9) | 2 (9) | 3 (9) | >.99 |
Follow-up and survival, n | 70 | 23 | 47 | |
Median follow-up, months | 48 | 43.5 | 48 | |
Median PFS, months | NR | NR | 6.6 | |
Median OS, months | NR | NR | 10.9 |
Data are presented as n (%) of patients, unless otherwise indicated.
ASCT, autologous stem cell transplantation; HL, Hodgkin lymphoma; NA, not assessed; NR, not reached; PR, partial response; RT, radiation therapy.
Missing data (n = 1).