Table 3.
Histopathological data for the entire cohort. Staging of endometriosis patients was based on intra-operative findings according to the American Society of Reproductive Medicine staging system [31]
| No. of patients | ||
|---|---|---|
| No NACT | NACT | |
| Ovarian cancers | ||
| High-grade serous | 33 | 43 |
| Low-grade serous | 5 | – |
| Primary peritoneal serous | – | 1 |
| Mucinous | 10 | – |
| Endometrioid | 9 | – |
| Clear cell | 8 | – |
| Carcinosarcoma | 4 | 1 |
| Anaplastic | 1 | – |
| Immature teratoma | 1 | – |
| Benign controls | ||
| Ovarian cysts (non-endometriomas) | ||
| Cystadenomas, fibromas, cystadenofibromas | 71 | |
| Mature cystic teratomas | 13 | |
| Follicular | 3 | |
| Haemorrhagic | 2 | |
| Struma ovarii | 2 | |
| Brenner | 1 | |
| Sertoli-Leydig | 1 | |
| Indeterminate | 2 | |
| Endometriosis (including endometriomas) | ||
| Stage 1 | 16 | |
| Stage 2 | 9 | |
| Stage 3 | 19 | |
| Stage 4 | 28 | |
| Uterine fibroids and/or adenomyosis | 69 | |
| Pelvic inflammatory disease | 9 | |
| Endometrial/cervical polyps | 8 | |
| Hydrosalpinx/paratubal cysts | 7 | |
| Uterine prolapse | 3 | |
| Peritoneal leiomyomatosis | 1 | |
| Endometrial hyperplasia | 1 | |
| Cervical intraepithelial neoplasia (CIN) | 1 | |
| Normal (no pathology identified) | 41 | |
NACT neo-adjuvant chemotherapy