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. 2021 Jul 13;413(21):5349–5360. doi: 10.1007/s00216-021-03509-y

Table 3.

Concentrations of methylamines (μmol/L) in spiked and non-spiked food samples and the calculated average

Compound Csample Cadded Cfound Recovery (%) Average recovery (%±RSD)
(mg/100g FW)
Meatball
TMA 0 1.1 1.1 100.3±0.1 97.9±4.9
2.8 2.6 95.4±6.8
TMAO 0 1.8 1.2 83.3±5.6 82.4±3.6
3.5 2.9 81.5±2.9
Choline 31.5 19.8 53.1 109.6±3.3 101.6±11.5
48.7 76.8 93.7±11.5
Betaine 9.7 4.4 14.5 105.9±4.8 100.6±11.1
10.9 20.2 95.5±15.5
Total carnitine 11.3 6.1 17.9 107.2±0.1 97.8±12.4
15.1 24.6 88.5±10.7
Egg
TMA 0 0.7 0.68 93.1±2.7 94.7±2.8
1.3 1.27 96.4±2.4
TMAO 0 0.9 0.7 71.8±3.2 75.8±7.1
1.7 1.3 79.8±0.9
Betaine 1.2 1.5 2.6 98.1±5.2 96.1±5.5
2.6 3.5 93.9±6.8
Choline 260.6 64.7 320.3 92.2±4.3 95.5±4.8
116.5 375.9 98.9±2.2
l-Carnitine 0 2.0 1.6 79.6±5.9 82.1±4.7
3.6 3.1 84.7±1.9
Creatinine 0 1.4 1.0 71.5±9.5 79.8±10.7
2.5 2.2 88.1±7.7

TMA, trimethylamine; TMAO, trimethylamine N-oxide. Cfound, mean content in the spiked sample; Csample, mean content in the sample without spiking; Cadded, content added to the sample. Contents are means of duplicate samples (± relative percentage difference). Further details are described in “Quality control of analytical method” section

Recovery (R)=(Cfound−Csample)/Cadded