Table 4.

Population estimates (typical values), standard deviation of the random effects and additional parameters obtained from fitting normalized FT4 data with the final PMX model Eqs. (4)–(7)

Parameter name	Description	Unit	Estimate (r.s.e.a)
Population estimates (fixed effects)
$k_a$	Absorption rate	1/day	20 fix
$k_{\mathit{el}}$	Elimination rate	1/day	0.1 fix
$f_V$	Multiplicative factor	l	4.96 (3.7)
${\beta }_W$	Power exponent	–	0.753 (6.6)
$k_{\mathit{endo}}$	Endogenous production rate	nmol/day	3.66 (15.7)
Standard deviation of the random effects
${\omega }_{f_V}$			0.249 (11.9)
${\omega }_{{\beta }_W}$			0.404 (15.8)
${\omega }_{k_{\mathit{endo}}}$			1.12 (11.1)
Additional parameters and values
Prop. residual error			0.228 (4.2)
− 2LL value			3268

^aRelative standard error